A cozy and satisfying classic, Chicken Biscuit Casserole is a family-favorite comfort dish that brings together tender chicken, creamy sauce, hearty vegetables, and fluffy biscuits all baked to golden perfection. It’s simple to make and ideal for busy weeknights or laid-back weekends.

Why You’ll Love This Recipe

This casserole is the definition of comfort food. It’s warm, creamy, and filling—perfect for feeding a hungry household. With minimal prep time and the use of pantry staples, it’s also incredibly convenient. The flaky, buttery biscuits on top soak up just enough of the savory sauce while maintaining their golden, crispy tops, creating a balanced texture in every bite. Plus, it’s easy to customize based on what you have on hand.

ingredients

(Tip: You can find the complete list of ingredients and their measurements in the recipe card below.)

2 cups cooked chicken (shredded or diced)
1 can (10.5 oz) cream of chicken soup
1 cup chicken broth
1 cup mixed vegetables (such as peas, carrots, and corn)
1 can (16.3 oz) refrigerated biscuits (or about 12 biscuits)
1/2 teaspoon garlic powder
1/2 teaspoon onion powder
1/2 teaspoon salt
1/4 teaspoon black pepper
1 cup shredded cheese (optional)

directions

Preheat the oven to 350°F (175°C) and grease a 9×13 inch baking dish.
Combine the filling: In a large bowl, mix the cooked chicken, cream of chicken soup, chicken broth, mixed vegetables, garlic powder, onion powder, salt, and pepper until well combined.
Assemble the casserole: Pour the chicken mixture into the prepared baking dish and spread it evenly. If desired, sprinkle shredded cheese over the top.
Prepare the biscuits: Cut each refrigerated biscuit into quarters and evenly distribute them on top of the chicken mixture.
Bake for 25–30 minutes, or until the biscuits are golden brown and the filling is hot and bubbly.
Cool and serve: Let the casserole rest for a few minutes before serving.

Servings and timing

This recipe serves 6 people.
Prep time: 10 minutes
Bake time: 25–30 minutes
Total time: 35–40 minutes

Variations

Cheesy Version: Stir cheese directly into the filling for an extra creamy texture.
Spicy Twist: Add a pinch of cayenne pepper or a few dashes of hot sauce to the filling for heat.
Different Soup Base: Use cream of mushroom or cream of celery soup for a variation in flavor.
Homemade Biscuits: If you prefer, use homemade biscuit dough instead of canned.
Vegetarian Option: Substitute chicken with mushrooms or plant-based chicken and use vegetable broth.

storage/reheating

Store leftovers in an airtight container in the refrigerator for up to 3 days. Reheat individual portions in the microwave or reheat the entire casserole in the oven at 350°F (175°C) until warmed through, loosely covered with foil to prevent the biscuits from over-browning. Avoid freezing once baked, as the biscuits may become soggy.

FAQs

Can I use rotisserie chicken?

Yes, rotisserie chicken is a great time-saving option and adds extra flavor.

Can I make this ahead of time?

You can prepare the filling ahead and store it in the fridge. Add the biscuits just before baking.

What vegetables work best in this casserole?

Peas, carrots, corn, and green beans all work well, either fresh, frozen, or canned.

Do I need to cook the vegetables before adding them?

If using frozen or canned vegetables, no pre-cooking is needed. For fresh vegetables, lightly steam or sauté before adding.

Can I use homemade biscuit dough?

Yes, homemade dough can be used. Just ensure the dough is rolled out and cut to similar size pieces for even baking.

Why are my biscuits still doughy on the bottom?

Ensure the filling is not too liquidy and spread the biscuit pieces evenly so they cook properly. Bake uncovered until the biscuits are golden.

Can I add herbs for more flavor?

Yes, dried thyme, parsley, or rosemary are great additions to enhance the dish.

Is it possible to make this casserole dairy-free?

Use a dairy-free cream soup, omit the cheese, and choose a non-dairy biscuit alternative.

What can I serve with this casserole?

A side salad or steamed green vegetables complement it well and balance the richness.

Can I freeze the unbaked casserole?

You can freeze the filling separately, but it’s best to add the biscuits fresh before baking to maintain texture.

Conclusion

Chicken Biscuit Casserole is a crowd-pleasing, comforting meal that’s easy to prepare and perfect for any night of the week. Whether you’re cooking for your family or looking for a dish to share, this casserole delivers in flavor, texture, and heartiness. Customizable and make-ahead friendly, it’s sure to become a regular in your recipe rotation.